Neil C. Boland, MD, FACOG, NCMP
Maria De La Luz Nieto, MD, FACOG, FPMRS
Michelle J. Veltri, MSN, APRN, A-GNP-C

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BHRT Literature Categories

Important Published Medical Literature

for Physician and Patient Reference (see BHRT Matrix in next drop down)
The Matrix includes 127 landmark studies, divided into:
  1. Category, see below
  2. Topic
  3. Level of Evidence:
    • 1A – Randomized Controlled Trials (strongest evidence)
    • 1B – Individual Randomized Controlled Trials
    • 2 – Cohort Study
    • 3 – Case Controlled Study
    • 4 – Expert Opinion (weakest evidence)
  4. Impact Factor: How Often Study is Cited / or Journal Prestige
  5. 37% of these papers include Pellet Evaluation as Designated
  6. Brief Comment about Study

Study Categories

Female

  • Safety and Efficacy (testosterone and estrogen)
  • Safety and Efficacy (testosterone only)
  • Breast Cancer
  • Cardiovascular Effects
  • Lipid Effects
  • Bone Density Effects
  • Coagulation Effects
  • Cognitive Effects
  • Pharmacokinetic Effects
  • Sexual Function
  • Aesthetics
  • Diabetes
  • Hypertension Effects

Male

  • Testosterone Effect Onset
  • Safety and Efficacy (Testosterone)
  • Prostate Cancer
  • Bone Density Effects
  • Cardiovascular Effects
  • Lipid Effects
  • Psychosomatic Effects
  • Estradiol Effects on Mortality
  • Insulin Resistance
  • Testosterone Pharmacokinetics
  • Secondary Erythrocytosis
  • DVT / VTE / Pulmonary Embolus Effects